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医学研究文献综述工作流

根据研究问题组织检索、筛选、证据整理和综述,保留引用核查、研究限制和透明的选择过程。

开源精选医疗业务15 个文件50,135 Stars浏览次数 1K-Dense-AI/scientific-agent-skills MIT版本 a1043ef
开始使用

适用环境:Python 3.10+ with requests; network for DOI checks and searches. Optional parallel-cli requires Parallel authentication. PDF export needs Pandoc and XeLaTeX; AI schematics need OPENROUTER_API_KEY.

输入资料
明确的医学研究问题与范围 可取得的实际文献及检索条件 阅读本节完整说明
交付内容
有引用依据的综述材料 检索筛选与证据记录 阅读本节完整说明
  1. 获取完整包,保留配套文件的目录结构。
  2. 按照原文准备所需工具、依赖与输入资料。
  3. 阅读对应使用步骤与输入输出说明,在自己的环境中验证结果。

使用提示摘自原文,配套文件保留来源版本;实际运行条件以各包说明为准。

正文

获取原文件

references/example_workflow.md

Illustrative end-to-end recipe, not an executed review. Run from the skill directory; populate the protocol, normalized search records, bibliography, and CSL file before the dependent commands. Dates below are a deliberately historical 2015-2024 interval.

Example Workflow

Complete workflow for a biomedical literature review:

# 1. Create review document from template
mkdir -p sources styles
cp assets/review_template.md crispr_sickle_cell_review.md

# 2. Optional supplementary discovery (authenticated Parallel account)
parallel-cli search "CRISPR Cas9 sickle cell disease gene therapy efficacy" \
  -q "CRISPR" -q "sickle cell" -q "gene therapy" \
  --json --max-results 10 --excerpt-max-chars-total 27000 \
  --include-domains "scholar.google.com,arxiv.org,pubmed.ncbi.nlm.nih.gov,semanticscholar.org,biorxiv.org,nature.com,science.org,cell.com,pnas.org,nih.gov" \
  -o sources/litreview_crispr_scd-academic.json

parallel-cli search "CRISPR sickle cell disease clinical trials treatment" \
  -q "CRISPR" -q "sickle cell" \
  --json --max-results 10 --excerpt-max-chars-total 27000 \
  -o sources/litreview_crispr_scd-general.json

# 3. Search specialized databases using appropriate skills
# - Use PubMed E-utilities and bioRxiv/medRxiv search or date-metadata APIs
# - Use direct API access for arXiv, Semantic Scholar
# - Save all pages and counts; document any API caps or failed requests
# - Normalize into a JSON array; keep raw exports and provenance

# 4. Process your normalized combined_results.json; raw API envelopes will fail
python scripts/search_databases.py combined_results.json \
  --deduplicate \
  --year-start 2015 \
  --year-end 2024 \
  --format markdown \
  --output search_results.md \
  --summary

# 5. Screen results and extract data
# - Request extracts with --full-content; obtain original reports and record failures
# - Use independent final full-text decisions and retain exclusion reasons
# - Track records, reports, studies, and overlapping participants separately
# - Extract key data into the review document
# - Organize by themes

# 6. Write the review following template structure
# - Introduction with clear objectives
# - Detailed methodology section
# - Results organized thematically
# - Critical discussion
# - Clear conclusions

# 7. Check DOI registration/metadata, then manually verify identity and claim support
python scripts/verify_citations.py crispr_sickle_cell_review.md

# Review the citation report
cat crispr_sickle_cell_review_citation_report.json

# Investigate missing/inconclusive results; transient failures do not invalidate citations
python scripts/verify_citations.py crispr_sickle_cell_review.md

# 8. Render after supplying bibliography, local CSL, and [@key] citations
# For manually typed references, omit those options; text will not be restyled
python scripts/generate_pdf.py crispr_sickle_cell_review.md \
  --bibliography crispr_sickle_cell_review.bib --csl styles/nature.csl \
  --output crispr_sickle_cell_review.pdf

# 9. Review final PDF and markdown outputs

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