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临床指南检索与版本追溯

按临床问题检索指南与推荐依据，登记机构、发布日期、适用人群和来源，供专业人员核查当前版本。

开源精选医疗业务5 个文件1,738 Stars浏览次数 0mims-harvard/ToolUniverse Apache-2.0版本 8c6ed47
获取完整包获取 SKILL.md
开始使用

下载前阅读 SKILL.md 中的使用条件，并确认所用工具支持对应能力。

输入资料
临床问题、地区与人群 可用指南来源及接口权限 阅读本节完整说明
交付内容
指南证据资料 版本、适用范围和来源记录 阅读本节完整说明
  1. 获取完整包，保留配套文件的目录结构。
  2. 按照原文准备所需工具、依赖与输入资料。
  3. 阅读对应使用步骤与输入输出说明，在自己的环境中验证结果。

使用提示摘自原文，配套文件保留来源版本；实际运行条件以各包说明为准。

正文

获取原文件

TOOLS_REFERENCE.md

Complete parameter reference for all 41 tools across 4 JSON config files. All parameters listed are verified by live API testing.

unified_guideline_tools.json (14 tools)

WHO_Guidelines_Search

  • Parameters: query (str, required), limit (int, required)
  • Returns: envelope {status, data: [...], metadata: {total, retrieved, returned, truncated}}; rows {title, url, description, content, source}
  • Note: Answers from a WHO health-topic page when the query names one, otherwise from a WHO IRIS text search; there is no generic fallback, so an empty data means WHO has nothing matching

WHO_Guideline_Full_Text

  • Parameters: url (str, required)
  • Returns: dict with guideline text (or PDF link)

CMA_Guidelines_Search

  • Parameters: query (str, required), limit (int, required)
  • Returns: list of {title, url, description, content, date}

SIGN_search_guidelines

  • Parameters: query (str, required — NOT q), limit (int, optional)
  • Returns: list of {number, title, topic, published, url}

SIGN_list_guidelines

  • Parameters: topic (str, optional — one of SIGN's topic names, e.g. 'Cardiovascular', 'Eye'; an unknown topic returns an error listing them), limit (int, optional)
  • Returns: list of SIGN guidelines

CTFPHC_list_guidelines

  • Parameters: limit (int, optional)
  • Returns: list of {title, url, year}

CTFPHC_search_guidelines

  • Parameters: query (str, required — NOT q), limit (int, optional)
  • Returns: list of {title, url, year}

TRIP_Database_Guidelines_Search

  • Parameters: query (str, required), limit (int, required), search_type (str, required — must be 'guidelines')
  • Returns: envelope {status, data: [...], metadata: {total, retrieved, returned, truncated}}; rows {title, url, description, content, publication}

OpenAlex_Guidelines_Search

  • Parameters: query (str, required), limit (int, required), year_from (int, optional), year_to (int, optional)
  • Returns: envelope {status, data: [...], metadata: {total, retrieved, returned, truncated}}; rows {title, authors, institutions, year, doi}

EuropePMC_Guidelines_Search

  • Parameters: query (str, required), limit (int, required)
  • Returns: envelope {status, data: [...], metadata: {total, retrieved, returned, truncated}}; rows {title, pmid, pmcid, doi, authors, abstract, publication_type}

PubMed_Guidelines_Search

  • Parameters: query (str, required), limit (int, optional); set NCBI_API_KEY in the environment for higher rate limits
  • Returns: envelope {status, data: [...], metadata: {total, retrieved, returned, truncated}}; rows {title, pmid, abstract, publication_types}

NICE_Clinical_Guidelines_Search

  • Parameters: query (str, required), limit (int, required)
  • Returns: envelope {status, data: [...], metadata: {total, retrieved, returned, truncated}}; rows {title, url, summary, content, date}

NICE_Guideline_Full_Text

  • Parameters: url (str, required)
  • Returns: dict with guideline text (may be empty; try .../chapter/Recommendations URL)

cpic_tools.json (15 tools)

All CPIC tools return dict-wrapped: access via r.get('data', []) or r.get('data', {}).

CPIC_get_gene_info

  • Parameters: genesymbol (str, required)
  • Returns: dict {data: {symbol, name, locus, ...}}
  • Example: CPIC_get_gene_info(genesymbol='CYP2D6')

CPIC_get_gene_drug_pairs

  • Parameters: genesymbol (str, required), limit (int, optional)
  • Returns: dict {data: [{genesymbol, drugid, cpiclevel, pgkbcalevel, usedforrecommendation}, ...]}
  • Note: cpiclevel A/B/C/D — A = strongest evidence

CPIC_list_guidelines

  • Parameters: limit (int, optional)
  • Returns: dict {data: [{name, guidelineId, url, ...}, ...]}
  • Use: Find guidelineId for calling CPIC_get_recommendations

CPIC_get_recommendations

  • Parameters: guideline_id (int, required — NOT genesymbol), limit (int, optional)
  • Returns: dict {data: [{phenotype, recommendation, activity_score, ...}, ...]}
  • ⚠️ CRITICAL: Parameter is guideline_id (integer from CPIC_list_guidelines), NOT gene symbol
  • Note: Returns duplicate records per allele combo — deduplicate by phenotype before presenting
  • Example: CPIC_get_recommendations(guideline_id=100416, limit=20)

CPIC_get_alleles

  • Parameters: genesymbol (str, required), limit (int, optional)
  • Returns: dict {data: [{haplotype_name, clinicalfunctionalstatus, ...}, ...]}
  • ⚠️ Use clinicalfunctionalstatus — not functionalstatus (always null)

CPIC_get_drug_info

  • Parameters: drugname (str, required)
  • Returns: dict {data: {name, rxNormId, ...}}
  • Example: CPIC_get_drug_info(drugname='codeine')

CPIC_search_gene_drug_pairs

  • Parameters: genesymbol (str, required with PostgREST syntax), limit (int, optional)
  • ⚠️ CRITICAL: Use PostgREST filter: genesymbol='eq.CYP2D6' (not just 'CYP2D6')
  • Example: CPIC_search_gene_drug_pairs(genesymbol='eq.CYP2D6', limit=5)

CPIC_list_drugs

  • Parameters: limit (int, optional)
  • Returns: dict {data: [{name, rxNormId, ...}, ...]}

CPIC_list_genes

  • Parameters: limit (int, optional)
  • Returns: dict {data: [{symbol, name, ...}, ...]}

CPIC_search_drugs

  • Parameters: name (str, required)
  • Returns: dict {data: [...]}

CPIC_get_guideline

  • Parameters: guideline_id (int, required)
  • Returns: dict {data: {name, url, ...}}

CPIC_get_gene_phenotypes

  • Parameters: genesymbol (str, required)
  • Returns: dict {data: [...]}

CPIC_get_publication

  • Parameters: pmid (str, required)
  • Returns: dict {data: {...}}

CPIC_list_publications

  • Parameters: limit (int, optional)
  • Returns: dict {data: [...]}

CPIC_get_frequency_data

  • Parameters: genesymbol (str, required)
  • Returns: dict {data: [...]}

ada_aha_nccn_tools.json (18 tools)

ADA_list_standards_sections

  • Parameters: none
  • Returns: list of ADA Standards of Care sections with PMIDs

ADA_search_standards

  • Parameters: query (str, required), limit (int, required)
  • Returns: list of {title, ...}
  • Note: Use broad medical terms. Filter: '[corp] American Diabetes Association'[Author]

ADA_get_standards_section

  • Parameters: section_number (int, required)
  • Returns: dict with abstract (not full PMC text)

ADA_get_full_standard

  • Parameters: pmid (str, required)
  • Returns: dict with full text content

AHA_ACC_search_guidelines

  • Parameters: query (str, required), limit (int, required)
  • Returns: list directly — [{title, ...}]
  • Example: AHA_ACC_search_guidelines(query='heart failure management', limit=5)

AHA_list_guidelines

  • Parameters: limit (int, required)
  • Returns: list of recent AHA guidelines

ACC_list_guidelines

  • Parameters: limit (int, required)
  • Returns: list of recent ACC guidelines

AHA_ACC_get_guideline

  • Parameters: pmid (str, required)
  • Returns: dict with full guideline text from PMC

AHA_search_statements

  • Parameters: query (str, required), limit (int, required)
  • Returns: list

ACC_search_guidelines

  • Parameters: query (str, required), limit (int, required)
  • Returns: list

NCCN_list_patient_guidelines

  • Parameters: limit (int, required)
  • Returns: list of {cancer_type, url, category}
  • ⚠️ Field is cancer_type, NOT title

NCCN_search_guidelines

  • Parameters: query (str, required), limit (int, required)
  • Returns: list of JNCCN PubMed abstracts
  • Note: Returns PubMed articles about NCCN guidelines, not proprietary guideline text

NCCN_get_patient_guideline

  • Parameters: url (str, required — full URL string)
  • Returns: dict with patient guideline text
  • ⚠️ CRITICAL: Pass full URL, NOT integer ID
  • Example: NCCN_get_patient_guideline(url='https://www.nccn.org/patientresources/patient-resources/guidelines-for-patients/guidelines-for-patients-details?patientGuidelineId=61')

NCI_search_cancer_resources

  • Parameters: q (str, required — NOT query), size (int, required — NOT limit)
  • Returns: dict → r.get('data', {}).get('results', []) gives list
  • ⚠️ NOTE: This is a catalog of bioinformatics tools/datasets, NOT clinical guidelines

NCI_list_cancer_types

  • Parameters: limit (int, optional)
  • Returns: list

NCI_get_cancer_resource

  • Parameters: resource_id (str, required)
  • Returns: dict

MAGICapp_list_guidelines

  • Parameters: limit (int, required)
  • Returns: dict → r.get('data', []) gives list of {name, guidelineId, ...}
  • ⚠️ Field is name, NOT title

MAGICapp_get_guideline

  • Parameters: guideline_id (str, required)
  • Returns: dict → r.get('data', {}) gives guideline details

sign_ctfphc_tools.json (15 tools)

(SIGN and CTFPHC tools listed above in unified_guideline_tools.json section also appear here — same interface)

MAGICapp_get_recommendations

  • Parameters: guideline_id (str, required)
  • Returns: dict → r.get('data', []) gives list of recommendations

MAGICapp_get_sections

  • Parameters: guideline_id (str, required)
  • Returns: dict → r.get('data', []) gives list of sections

Quick Decision Guide

Clinical question type Start with
General disease guideline NICE + TRIP + EuropePMC
UK-specific NICE + SIGN
Canadian CMA + CTFPHC
International EuropePMC + OpenAlex
Cardiology AHA_ACC_search_guidelines + AHA_list_guidelines
Oncology NCCN_search_guidelines + NCCN_list_patient_guidelines
Diabetes ADA_list_standards_sections + ADA_search_standards
Pharmacogenomics CPIC workflow (gene_info → drug_pairs → list_guidelines → recommendations)
Living/current MAGICapp_list_guidelines
Research tools/datasets NCI_search_cancer_resources (not clinical guidelines!)

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